Carbonic Acid 2,5-Dioxopyrrolidin-1-yl (S)-Tetrahydrofuran-3-yl Ester - Names and Identifiers
Carbonic Acid 2,5-Dioxopyrrolidin-1-yl (S)-Tetrahydrofuran-3-yl Ester - Physico-chemical Properties
Molecular Formula | C9H11NO6
|
Molar Mass | 229.19 |
Density | 1.45g/cm3 |
Melting Point | 114-117°C |
Boling Point | 338.7°C at 760 mmHg |
Flash Point | 158.7°C |
Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Ether, Methanol |
Vapor Presure | 9.63E-05mmHg at 25°C |
Appearance | Solid |
Color | Off-White |
Storage Condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
Refractive Index | 1.536 |
Carbonic Acid 2,5-Dioxopyrrolidin-1-yl (S)-Tetrahydrofuran-3-yl Ester - Introduction
(S)-Tetrahydrofuranyl succinimidyl carbonate is an organic compound with the chemical formula C10H15NO6. It is a white to pale yellow solid, soluble in some organic solvents, such as ethanol and dichloromethane.
(S)-tetrahydrofuryl succinimidyl carbonate is a chiral compound with good catalytic properties. It is often used as a chiral catalyst to participate in organic synthesis reactions, especially asymmetric synthesis reactions. It can be used to catalyze the hydroxyl esterification of esters, the alcoholysis of esters, and the condensation of amines with aldehydes.
The method for preparing (S)-tetrahydrofuryl succinimidyl carbonate is generally to react (S)-phenylsuccinic acid ester with acetonitrile, followed by imidization to form (S)-N-phenylbromosuccinimidyl ester, which is finally subjected to carbonation to obtain the target product.
Regarding safety information, there is currently no separate report specifically for (S)-tetrahydrofuryl succinimidyl carbonate. However, as a chemical, its use needs to follow general safety practices. During use, personal protective equipment such as protective gloves and goggles should be worn to avoid inhalation of dust or skin contact. When stored, it should be kept in a dry, cool place, away from fire and oxidizing agents. If accidentally splashed into the skin or eyes, rinse immediately with plenty of water and seek medical advice.
Last Update:2024-04-10 22:29:15